Fallout 4 Anniversary Edition is a comprehensive re-release of the base Fallout 4 game, including its three main expansions (Automaton, Far Harbour, Nuka World) and three workshop DLCs (Contraptions, Vault-Tec, Wasteland). It also features over 150 Creation Club DLCs released to date, plus new Creations exclusive to this edition. These additions encompass a wide variety of content such as new quests, companions, weapons, armor, paint jobs for weapons, armor, power armor, and Pip-Boys, as well as new dog breeds, player homes, and settlement-building options.

Players can access the Creation Club content by purchasing the Anniversary Edition or the Creations Bundle, then downloading the included Creations from the main menu. The DLCs offer diverse enhancements, including short questlines with unique rewards, new companions requiring quest completion, and extensive customization options for gear and settlements. This edition aims to enrich the Fallout 4 experience with a vast array of official add-ons, providing both new and returning players with fresh content to explore in the wasteland.